Term: Cannabinol (CBN)
Cannabinol (or CBN) is a non-psychoactive cannabinoid found only in trace amounts in Cannabis and is mostly found in aged Cannabis. Pharmacologically relevant quantities are formed as a metabolite of Tetrahydrocannabinol (or THC). CBN acts as a partial agonist at the CB1 Receptors, but has a higher affinity to CB2 Receptors; however, it has lower affinities relative to THC. Degraded or oxidized cannabis products, such as low-quality baled cannabis and traditionally produced hashish, are high in CBN, but modern production processes minimize the formation of CBN.