This Is Your Brain on Drugs

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This Is Your Brain on Drugs (Wikipedia)

This Is Your Brain on Drugs was a large-scale US anti-narcotics campaign by Partnership for a Drug-Free America (PDFA) launched in 1987, that used three televised public service announcements (PSAs) and a related poster campaign.

The Partnership used a simple advertisement showing an egg in a frying pan, similar to this photo, suggesting that the effect of drugs on a brain was like an egg on a hot pan.
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