Humulene was the first terpene found in hops. Its aroma contains earthy, woody, and spicy notes. Besides cannabis, it can be also found in clove, sage, and black pepper. It has a variety of medical properties. Early research has shown humulene to be anti-proliferative, meaning it prevents cancer cells from growing. Also, it proved to be effective in suppressing appetite, making it a potential weight loss tool. Furthermore, like many other cannabis terpenes mentioned above, it also reduces inflammation, relieves pain, and fights bacterial infections.