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Something that reduces the effectiveness of the immune system, which may be endogenous or exogenous and which may occur as an adverse reaction or may be the intended result of treatment.

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Immunosuppressant (Wikipedia)

Prednisone
Dexamethasone

Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system.

Immunosuppressant (Wiktionary)

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Immunosuppressive agent, immune suppressant, immunosuppressive drug, immune system inhibitor, immunomodulator
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